Table 1.

Studies on cyclosporine effect on recurrent FSGS.

Reference	Study Design	Treatments	Incidence of FSGS recurrence/°Remission Rate
Prevention
Banfi G, et al. (52)	Retrospective	− Steroids + AZA (n=6)	2 (33%)
		− Steroids + CsA (n=19)	10 (55%)
Schwarz A, et al. (43)	Retrospective	− Steroids + AZA (n=7)	1 (14%)
		− Steroids + CsA (n=8)	2 (25%)
Inguilli E Tejani A (53)	Retrospective	− Steroids + AZA (n=22)	4 (18%)
		− Steroids + CsA (n=18)	2 (11%)
Treatment°
Ingulli E, et al. (42)	Case report	Progressive uptitration of oral CsA doses	1 Complete and 1 partial remission
Salomon R, et al. (40)	Retrospective	I.v. CsA (n=16). trough levels: 250–350ng/mL	Complete remission: 13 (81%) Partial remission: 2 (13%)
Raafat RH, et al. (41)	Retrospective	Oral CsA doses were uptitrated until proteinuria reduction or serum creatinine elevation (n=16)	Complete remission: 11 (65%) Partial remission: 2 (12%)
Canaud G, et al. (72)	Prospective cohort	I.v. CsA, combined with high-dose steroids and intensive plasmapheresis (n=10)	Complete remission: 9 (90%) [Incidence of complete remission in a control historical cohort: 5/19 (27%)]

AZA: azathioprine; CsA: cyclosporine.