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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2013 Jan 3;52(2):172–183.e8. doi: 10.1016/j.jaac.2012.10.005

Table 3.

Intraclass Correlations and Estimated Heritabilities Between Twins Within Latent Classes at Ages 7, 10, and 12

Twin Type n pairs Class

Low or No Symptom Defiant Irritable High Symptom
Age 7
MZM 605 0.65 0.643 0.333 0.476
DZM 679 0.457 0.349 0.014 0.137
MZF 675 0.617 0.63 0.252 0.405
DZF 622 0.435 0.415 0.016 0.134
DOS 1223 0.421 0.505 0.079 0.175
Heritability male 0.386 0.588 0.333 0.476
Heritability female 0.364 0.43 0.252 0.405

Age 10
MZM 498 0.69 0.524 0.279 0.574
DZM 510 0.43 0.365 −0.009 0.244
MZF 637 0.711 0.658 0.395 0.522
DZF 513 0.503 0.477 0.081 0.179
DOS 1122 0.393 0.325 0.018 0.132
Heritability male 0.52 0.318 0.279 0.574
Heritability female 0.416 0.362 0.395 0.522

Age 12
MZM 488 0.636 0.494 0.31 0.39
DZM 459 0.571 0.377 0.155 0.185
MZF 580 0.748 0.623 0.45 0.411
DZF 423 0.608 0.374 0.123 0.108
DOS 920 0.531 0.445 0.245 0.236
Heritability male 0.13 0.234 0.31 0.39
Heritability female 0.28 0.498 0.45 0.411

Note: Heritability is calculated using Falconer’s formula, except in situations where genetic dominance may be present (monozygotic [MZ] correlation >= 2 × dizygotic [DZ] correlation) in which case the MZ correlation is used as the estimate.

DOS = dizygotic twins of opposite sex; DZF = dizygotic female; DZM = dizygotic male; MZM = monozygotic male; MZF = monozygotic female.