Table 3.
Intraclass Correlations and Estimated Heritabilities Between Twins Within Latent Classes at Ages 7, 10, and 12
Twin Type | n pairs | Class | |||
---|---|---|---|---|---|
| |||||
Low or No Symptom | Defiant | Irritable | High Symptom | ||
Age 7 | |||||
MZM | 605 | 0.65 | 0.643 | 0.333 | 0.476 |
DZM | 679 | 0.457 | 0.349 | 0.014 | 0.137 |
MZF | 675 | 0.617 | 0.63 | 0.252 | 0.405 |
DZF | 622 | 0.435 | 0.415 | 0.016 | 0.134 |
DOS | 1223 | 0.421 | 0.505 | 0.079 | 0.175 |
Heritability male | 0.386 | 0.588 | 0.333 | 0.476 | |
Heritability female | 0.364 | 0.43 | 0.252 | 0.405 | |
| |||||
Age 10 | |||||
MZM | 498 | 0.69 | 0.524 | 0.279 | 0.574 |
DZM | 510 | 0.43 | 0.365 | −0.009 | 0.244 |
MZF | 637 | 0.711 | 0.658 | 0.395 | 0.522 |
DZF | 513 | 0.503 | 0.477 | 0.081 | 0.179 |
DOS | 1122 | 0.393 | 0.325 | 0.018 | 0.132 |
Heritability male | 0.52 | 0.318 | 0.279 | 0.574 | |
Heritability female | 0.416 | 0.362 | 0.395 | 0.522 | |
| |||||
Age 12 | |||||
MZM | 488 | 0.636 | 0.494 | 0.31 | 0.39 |
DZM | 459 | 0.571 | 0.377 | 0.155 | 0.185 |
MZF | 580 | 0.748 | 0.623 | 0.45 | 0.411 |
DZF | 423 | 0.608 | 0.374 | 0.123 | 0.108 |
DOS | 920 | 0.531 | 0.445 | 0.245 | 0.236 |
Heritability male | 0.13 | 0.234 | 0.31 | 0.39 | |
Heritability female | 0.28 | 0.498 | 0.45 | 0.411 |
Note: Heritability is calculated using Falconer’s formula, except in situations where genetic dominance may be present (monozygotic [MZ] correlation >= 2 × dizygotic [DZ] correlation) in which case the MZ correlation is used as the estimate.
DOS = dizygotic twins of opposite sex; DZF = dizygotic female; DZM = dizygotic male; MZM = monozygotic male; MZF = monozygotic female.