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. 2013 Jan 30;3:844. doi: 10.1038/srep00844

Figure 2. Cartoon representation of the anandamide binding site and docking poses of TCM candidates within the binding site.

Figure 2

(a) Enlarged view of the docking site (green) within the modeled human FLAT protein. The front and back sides of the binding site are depicted in red and purple, respectively. (b) Front view of docking site with docked ligands. (9Z)-1-(5-pyridin-2-yl-1,3,4-oxadiazol-2-yl)octadec-9-en-1-one (control), Guineensine, and Retrofractamide A are shown in orange, blue, and green, respectively. Ser217 and Ile238 are amino acids found adjacent to the binding site. (c) Side view of docking site with docked ligands (45 degrees relative to b).