Skip to main content
. 2013 Jan 30;3:844. doi: 10.1038/srep00844

Figure 9. Contour of superimposed ligands to CoMFA and CoMSIA feature maps.

Figure 9

(a) The aromatic head and bend in the hydrophobic tail contoured to the steric favoring region (yellow), and the hydrophobic tail regions contoured to the steric disfavoring region in the CoMFA map. (b) In the CoMSIA map, ligand tail regions contoured to both the steric favoring (yellow) and disfavoring (green) regions. Aromatic heads of the ligands contoured to both the hydrophobic (gray) and hydrophilic (cyan) features. (9Z)-1-(5-pyridin-2-yl-1,3,4-oxadiazol-2-yl)octadec-9-en-1-one, Guineensine, and Retrofractamide A (green) are represented in blue, red, and green, respectively.