Table 8. Radius of gyration (Rg) calculated for the control and TCM candidates.
| Radius of Gyration (Rg; nm) | ||||||
|---|---|---|---|---|---|---|
| Control1 | Guineensine | Retrofractamide A | ||||
| Average | Maximum | Average | Maximum | Average | Maximum | |
| Protein | 2.596 | 4.184 | 3.100 | 4.700 | 2.170 | 2.292 |
| Mainchain | 2.562 | 4.153 | 3.152 | 4.794 | 2.163 | 2.299 |
| Sidechain | 2.602 | 4.188 | 3.093 | 4.685 | 2.172 | 2.291 |
| Backbone | 2.556 | 4.160 | 3.148 | 4.792 | 2.157 | 2.289 |
| C alpha | 2.561 | 4.165 | 3.153 | 4.792 | 2.162 | 2.292 |
| Ligand | 0.623 | 0.720 | 1.621 | 5.054 | 0.569 | 0.659 |
1Control: (9Z)-1-(5-pyridin-2-yl-1,3,4-oxadiazol-2-yl)octadec-9-en-1-one