Table 2. Pairwise Nei’s genetic distance (above diagonal) and ΦPT values (below diagonal) between the major dhps haplotypes in the DRC*.
SAKA | SGKA | SGEA | SGEG | AAKA | AGKA | |
---|---|---|---|---|---|---|
SAKA | 0.540 | 0.765 | 0.735 | 0.174 | 0.879 | |
SGKA | 0.133 | 0.746 | 0.978 | 0.371 | 0.133 | |
SGEA | 0.037 | 0.362 | 0.081 | 0.351 | 1.249 | |
SGEG | 0 | 0.380 | 0 | 0.509 | 1.220 | |
AAKA | 0 | 0.124 | 0.009 | 0 | 0.666 | |
AGKA | 0.032 | 0 | 0.217 | 0.588 | 0.008 |
Calculated using GenAlEx v6.5 using 149 specimens with pure (i.e. non-mixed) dhps haplotypes, using 999 permutations over full population and 99 permutations for pairwise comparisons39.
*ΦPT values with a p < 0.05 are indicated in italics and bold. Haplotypes are indicated by the amino acids at codons 436, 437, 540, and 581 of DHPS; mutant amino acids are underlined and bolded.