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Effect of temperature on 17-OHPC transport from primary human adult and fetal hepatocytes. The transport was evaluated at warm (37°C) and cold (4°C) temperatures. The results are expressed as 17-OHPC efflux relative to total 17-OHPC uptake (amount in media + cell lysate). Each bar represents the mean of triplicate treatments (±S.D.). Inhibition (statistically significant for *P < 0.05) of 17-OHPC efflux was observed in cold media.
