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Effect of cyclosporine (CyA) on taurocholate (TCA) uptake from primary human adult and fetal hepatocytes. The results are expressed as total TCA uptake in the presence of CyA normalized to the total uptake in the absence of CyA. Each bar represents the mean of triplicate treatments (±S.D.). Significant (*P < 0.05) inhibition of TCA efflux was observed in the presence of CyA.
