TABLE 2.
Total uptake of 17α-hydroxyprogesterone caproate in fetal and adult human hepatocytes
The total uptake was estimated by scintillation counting and calculated on the basis of total protein content. The results are expressed as mean (±S.D.).
Hepatocytes | Condition/Inhibitor | Total Uptake |
---|---|---|
pmol/mg protein | ||
Fetal | CyA | 304 ± 103 |
Fetal | No CyA | 284 ± 70 |
Adult | CyA | 494 ± 260 |
Adult | No CyA | 476 ± 171 |
Fetal | VER | 281 ± 47 |
Fetal | No VER | 263 ± 93 |
Adult | VER | 347 ± 86 |
Adult | No VER | 341 ± 81 |
Fetal | RIF | 241 ± 26 |
Fetal | No RIF | 267 ± 86 |
Adult | RIF | 565 ± 110 |
Adult | No RIF | 611 ± 146 |