TABLE 3.
Adjusted* Odds Ratios (and 95% Confidence Intervals) for Frequencies of Symptomatic OA Phenotypes by Race and by Gender (n=1650).
| Symptomatic OA Phenotype† | n | aOR (95% CI) for AA vs White | aOR (95% CI) for Men vs Women | Race and Gender stratified‡ |
|---|---|---|---|---|
| No sOA | 836 | -- | -- | White women: 1.0 (referent) |
| White men: 1.65 (1.28, 2.13) | ||||
| AA women: 1.57 (1.19, 2.07) | ||||
| AA men: 1.48 (1.05, 2.09) | ||||
| Hand Only | 64 | 0.19 (0.08, 0.49) | 0.50 (0.27, 0.91) | -- |
| Hip Only | 45 | 0.77 (0.39, 1.51) | 1.38 (0.75, 2.51) | -- |
| Knee Only | 162 | 1.78 (1.27, 2.50) | 0.85 (0.59, 1.22) | -- |
| LS Only | 195 | 0.90 (0.65, 1.25) | 1.48 (1.09, 2.01) | -- |
| Hand/Knee | 42 | 0.31 (0.13, 0.76) | 0.31 (0.13, 0.75) | -- |
| Hand/LS | 42 | -- | -- | White women: 1.0 (referent) |
| White men: 0.27 (0.10, 0.70) | ||||
| AA women: 0.07 (0.01, 0.51) | ||||
| AA men: 0.41 (0.12, 1.37) | ||||
| Knee/LS | 88 | -- | -- | White women: 1.0 (referent) |
| White men: 1.23 (0.69, 2.20) | ||||
| AA women: 1.92 (1.12, 3.29) | ||||
| AA men: 1.18 (0.52, 2.64 |
*
Adjusted for race, gender, age, and body mass index, only for those phenotypes affecting at least 40 persons
†
Mutually exclusive, referent is all other phenotypes
‡
Stratified by race and gender due to a significant (<0.2) race*gender interaction term: for no sOA p=0.02, for Hand/LS p=0.02, and for knee/LS p=0.17
BOLD indicates statistically significant results (aOR does not cross 1.0)
aOR=adjusted odds ratio, CI=confidence interval, AA=African American, LS=Lumbosacral Spine