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The HCV genome is typical of other positive-strand RNA viruses. The HCV genome contains structural proteins (C, E1, E2), proteins involved in virion morphogenesis (p7, NS2) and nonstructural proteins responsible for HCV genome replication (NS3, NS4A, NS4B, NS5A and NS5B). NS5A stands out as a unique feature of HCV compared to other positive-strand RNA viruses.
