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. 2012 Jul 30;6(3):406–414. doi: 10.4056/sigs.2826118

Table 4. Number of genes associated with the 25 general COG functional categories.

Code    Value    % agea     Description
J    160    3.39     Translation
A    1    0.02     RNA processing and modification
K    375    7.94     Transcription
L    419    8.87     Replication, recombination and repair
B     0    0.00     Chromatin structure and dynamics
D    47    1.00     Cell cycle control, mitosis and meiosis
Y    0    0.00     Nuclear structure
V    92    1.95     Defense mechanisms
T    222    4.70     Signal transduction mechanisms
M    116    2.46     Cell wall/membrane biogenesis
N    61    1.29     Cell motility
Z    1    0.02     Cytoskeleton
W    0    0.00     Extracellular structures
U    60    1.27     Intracellular trafficking and secretion
O    81    1.72     Posttranslational modification, protein turnover, chaperones
C    224    4.74     Energy production and conversion
G    150    3.18     Carbohydrate transport and metabolism
E    284    6.01     Amino acid transport and metabolism
F    77    1.63     Nucleotide transport and metabolism
H    103    2.18     Coenzyme transport and metabolism
I    79    1.67     Lipid transport and metabolism
P    125    2.65     Inorganic ion transport and metabolism
Q    34    0.72     Secondary metabolites biosynthesis, transport and catabolism
R    370    7.83     General function prediction only
S    240    5.08     Function unknown
-    1,686    35.70     Not in COGs

The total is based on the total number of protein coding genes in the annotated genome.