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. 2012 Jul 27;6(3):381–400. doi: 10.4056/sigs.2605792

Table 4. Number of genes associated with the 25 general COG functional categories.

Code       Value      %age       Description
J       224      3.6       Translation, ribosomal structure and biogenesis
A       RNA processing and modification
K       663      10.6       Transcription
L       152      3.2       Replication, recombination and repair
B       2      0.03       Chromatin structure and dynamics
D       213      3.4       Cell cycle control, cell division, chromosome partitioning
Y       Nuclear structure
V       244      3.9       Defense mechanisms
T       480      7.7       Signal transduction mechanisms
M       440      7.0       Cell wall/membrane/envelope biogenesis
N       130      2.1       Cell motility
Z       5      0.1       Cytoskeleton
W       0      0.0       Extracellular structures
U       41      0.7       Intracellular trafficking, secretion, and vesicular transport
O       331      5.3       Posttranslational modification, protein turnover, chaperones
C       415      6.6       Energy production and conversion
G       1,030      16.5       Carbohydrate transport and metabolism
E       788      12.6       Amino acid transport and metabolism
F       244      3.9       Nucleotide transport and metabolism
H       373      6.0       Coenzyme transport and metabolism
I       88      1.4       Lipid transport and metabolism
P       559      9.0       Inorganic ion transport and metabolism
Q       283      4.5       Secondary metabolites biosynthesis, transport and catabolism
R       872      14.0       General function prediction only
S       371      6.0       Function unknown
-       0      0.0       Not in COGs

The total is based on the total number of protein coding genes in the annotated genome. Data from [53].