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. 2012 Jul 20;6(3):415–426. doi: 10.4056/sigs.2846206

Table 4. Number of genes associated with the 25 general COG functional categories.

Code    Value     %agea       Description
J    0     0       Translation
A    0     0       RNA processing and modification
K    2     5       Transcription
L    3     7.5       Replication, recombination and repair
B    0     0       Chromatin structure and dynamics
D    0     0       Cell cycle control, mitosis and meiosis
Y    0     0       Nuclear structure
V    0     0       Defense mechanisms
T    2     5       Signal transduction mechanisms
M    1     2.5       Cell wall/membrane biogenesis
N    1     2.5       Cell motility
Z    0     0       Cytoskeleton
W    0     0       Extracellular structures
U    0     0       Intracellular trafficking and secretion
O    0     0       Posttranslational modification, protein turnover, chaperones
C    1     2.5       Energy production and conversion
G    0     0       Carbohydrate transport and metabolism
E    0     0       Amino acid transport and metabolism
F    0     0       Nucleotide transport and metabolism
H    0     0       Coenzyme transport and metabolism
I    0     0       Lipid transport and metabolism
P    0     0       Inorganic ion transport and metabolism
Q    0     0       Secondary metabolites biosynthesis, transport and catabolism
R    1     2.5       General function prediction only
S    3     7.5       Function unknown
-    28     70       Not in COGs

a) The total is based on the total number of protein coding genes in the annotated genome.