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. 2012 Jul 20;6(3):1–16. doi: 10.4056/sigs.2625821

Table 4. Number of genes associated with the 25 general COG functional categories.

Code      Value     %agea      Description
J      140     4.49      Translation
A      0     0      RNA processing and modification
K      149     4.78      Transcription
L      136     4.37      Replication, recombination and repair
B      0     0      Chromatin structure and dynamics
D      18     0.58      Cell cycle control, mitosis and meiosis
Y      0     0      Nuclear structure
V      44     1.41      Defense mechanisms
T      89     2.85      Signal transduction mechanisms
M      166     5.33      Cell wall/membrane biogenesis
N      7     0.22      Cell motility
Z      0     0      Cytoskeleton
W      0     0      Extracellular structures
U      41     1.32      Intracellular trafficking and secretion
O      67     2.15      Posttranslational modification, protein turnover, chaperones
C      134     4.30      Energy production and conversion
G      222     7.13      Carbohydrate transport and metabolism
E      155     4.98      Amino acid transport and metabolism
F      54     1.73      Nucleotide transport and metabolism
H      73     2.34      Coenzyme transport and metabolism
I      45     1.45      Lipid transport and metabolism
P      138     4.43      Inorganic ion transport and metabolism
Q      18     0.58      Secondary metabolites biosynthesis, transport and catabolism
R      281     9.03      General function prediction only
S      112     3.60      Function unknown
-      1,250     32.89      Not in COGs

a The total is based on the total number of protein coding genes in the annotated genome.