Figure 5.
IgM inhibition of the maturation of bone marrow-derived DC. Myeloid DC were pretreated with IgM (20 µg/ml) for an hour, then stimulated with LPS (1µg/ml) for 48 hours. Flow cytometry ananlysis was performed to observe the expression of MHC II, CD80 and CD86 in immature (left) and mature (Right) myeloid DC treated with (Blue) or without (Red) IgM (* p<0.05).