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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: J Immunol. 2012 Oct 12;189(10):4870–4880. doi: 10.4049/jimmunol.1201296

Figure 6. Characteristics of synaptic lytic granule motility that do not degranulate.

Figure 6

Comparative measurements of LysoTracker Red motility in lytic granules for which degranulation or no degranulation was observed. Length (A), track velocity (B), displacement (C), displacement rate (D), and persistence time (E) plotted for 10 granules observing no degranulation (LysoTracker Red only). Data is shown alongside measurements obtained from degranulation events previously illustrated in Figure 4 (i.e., the same results in Figure 3 for degranulating granules). The representative NK92 granule from Figure 5A is indicated in LysoTracker Red data set for comparison to the other granules measured, but for which image sequences are not shown (open diamond). F) Velocities of granules that degranulate (black) or do not (red) were measured at one minute intervals. Mean ± SD are depicted. The means of the LysoTracker Red data sets were not significantly different (p>0.05, two-tailed t test). Results are shown from 4 independent experiments.