Table 1.
Characterization of GbEN formulations by measuring entrapment efficiency and particle size (mean ± SD, n = 3)
| Formulation No | HLB value | Hydration temperature (°C) | Ratio (mol/mol) (surfactant: cholesterol) | Ratio (w/w) (GbE: carriers) | Entrapment efficiency (%) | Mean particle size (nm) |
|---|---|---|---|---|---|---|
| F1 | 11.0 | 60 | 1:0.5 | 9:100 | 57.7 ± 3.8 | 142.8 ± 19.1 |
| F2 | 11.5 | 70 | 1:0.5 | 12:100 | 44.1 ± 2.9 | 144.9 ± 15.6 |
| F3 | 12.0 | 80 | 1:0.5 | 15:100 | 46.3 ± 1.2 | 140.9 ± 18.0 |
| F4 | 11.0 | 60 | 1:0.75 | 12:100 | 47.3 ± 2.0 | 410.1 ± 20.3 |
| F5 | 11.5 | 60 | 1:0.75 | 15:100 | 44.7 ± 1.8 | 283.6 ± 21.2 |
| F6 | 12.0 | 70 | 1:0.75 | 9:100 | 38.7 ± 2.9 | 144.0 ± 7.7 |
| F7 | 11.0 | 70 | 1:1 | 15:100 | 54.4 ± 5.7 | 505.1 ± 49.5 |
| F8 | 11.5 | 80 | 1:1 | 9:100 | 51.1 ± 4.4 | 163.4 ± 10.6 |
| F9 | 12.0 | 80 | 1:1 | 12:100 | 47.7 ± 3.1 | 408.4 ± 30.8 |
| F10 | 11.0 | 60 | 1:1 | 15:100 | 50.0 ± 1.9 | 141.3 ± 11.9 |