Table 3.
Expression of SNAI2, TWIST1 and CDH1 in thyroid tumors by immunohistochemistry (positive/total cases)
| Antibody/tumor type | Normal thyroid | Follicular adenoma | Papillary thyroid carcinoma | Follicular variant of thyroid carcinoma | Follicular thyroid carcinoma | Anaplastic thyroid carcinoma |
|---|---|---|---|---|---|---|
| SNAI2a | 0/10 | 0/33 | 0/28 | 0/28 | 0/27 | 8/10 Diffuse 6/8 Focal 2/8 |
| TWIST1a | 0/10 | 0/33 | 0/28 | 0/28 | 0/27 | 5/10 All diffuse |
| CDH1b | 10/10 | 33/33 | 28/28 | 28/28 | 27/27 | 3/10 (30%) All diffuse |
a
Two-tailed χ2, P<0.0001.
b
Two-tailed Fisher’s exact test, P=0.026.