Table 1. Parameters from all the evaluated experiments.

Clinical signs score
Groups	Conjuntival redness	p	Conjuntival edema	p	Lid redness	p	Lid Edema	p	Mucus secretion	p
Vehicle	2.53±0.20		2.10±0.19		0.76±0.07		0.16±0.05		2.11±0.18
Azithromycin	1.88±0.19	<0.05	1.48±0.14	<0.05	0.40±0.07	<0.01	0.00±0.00	<0.05	1.43±0.19	<0.05

RNA expression
Groups	COX-2 (RQ)	p	IL-6 (RQ)	p	MMP-2 (RQ)	p	MMP-9 (RQ)	p	TNF-α (RQ)	p
Vehicle	1		1		1		1		1
Azithromycin	1.745	ns	1.038	ns	0.433	0.061	0.605	ns	0.828	ns

Protein analysis, macrophage infiltration and mucopolysacharide measurement
Groups	IL-6 (ng/µl)	p	NF-κβ (%)	p	MMP-2 activity (%)	p	PAS staining (pixels)	p	CD 68 (cell number)	p
Vehicle	2.03±0.45		100±3.4		100±6.2		429926±105314		134.5±29.6
Azithromycin	0.70±0.10	<0.05	84.18±3.3	<0.01	80.7±3.9	<0.05	154685±38542	<0.05	27.8±9.9	<0.05

Data are represented as mean± Standard Error of Mean (SEM) *p<0.05 versus vehicle.