Table 2. Cases, clinical isolates, and results of pneumococcal carriage and respiratory pathogen survey associated with Streptococcus pneumoniae serotype 15A outbreak, Rhode Island, USA, December 25, 2010–January 31, 2011*.
| Case status | Case no. | Onset date | Culture date, specimen and result | Chest imaging results | Treatment | Outcome | Carriage | Sero | Other pathogens by TAC† |
|---|---|---|---|---|---|---|---|---|---|
| IPD | S1 | Jan 9 | Jan 14, blood, S. pneumoniae 15A | Right upper lobe pneumonia | Moxifloxacin | Rec | Neg | Neg | |
| IPD | P1 | Jan 11 | Jan 25, blood, S. pneumoniae 15A | Negative | Ceftriaxone | Rec | Pos | 15A | Rhinovirus, adenovirus |
| Noninvasive pneumococcal disease | P2 | Jan 2 | Jan 28, otorrhea, S. pneumoniae 15A | Cefuroxime, topical ofloxacin | Rec | Pos | 15A | Mycoplasma pneumoniae | |
| Confirmed pneumonia | P3 | Jan 2 | Left lower lobe pneumonia | Amoxicillin/ clavulanate, azithromycin | Rec | Pos | NT‡ | Rhinovirus | |
| Confirmed pneumonia | S2 | Jan 5 | Left upper lobe pneumonia | Amoxicillin/ clavuanate, ciprofloxacin | Rec | NS | NS | ||
| Confirmed pneumonia | V1 | Jan 15 | Right basilar pneumonia | Moxifloxacin | Rec | NS | NS | ||
| Confirmed pneumonia | P4 | Jan 18 | Right lower lobe pneumonia | Ceftriaxone, ampicillin, amoxicillin | Rec | Neg | M. pneumoniae | ||
| Confirmed pneumonia | V2 | Feb 4 | Left lower lobe pneumonia | Doxycycline, levofloxacin | Rec | NS | NS | ||
| Confirmed pneumonia§ | V3 | Feb 23 | Left lower lobe pneumonia | Unk | Unk | NS | NS | ||
| Suspected pneumonia | S3 | Jan 11 | Azithromycin | Rec | NS | NS | |||
| Suspected pneumonia | P5 | Jan 13 | Clindamycin | Rec | Neg | Neg | |||
| Non-case | P6 | Neg | S. pyogenes | ||||||
| Non-case | P7 | Neg | Adenovirus | ||||||
| Non-case | P8 | Neg | Neg | ||||||
| Non-case | P9 | Pos | 34 | S. pyogenes | |||||
| Non-case | P10 | Neg | Neg | ||||||
| Non-case | P11 | Pos | 15A | Enterovirus | |||||
| Non-case | P12 | Pos | 15A | Neg | |||||
| Non-case | P13 | Pos | 11 A/D, 20 | S. pyogenes | |||||
| Non-case | P14 | Neg | Neg | ||||||
| Non-case | P15 | Pos | 15A | Rhinovirus, M. pneumoniae | |||||
| Non-case | P16 | Pos | 15A | M. pneumoniae | |||||
| Non-case | S4 | Neg | Rhinovirus | ||||||
| Non-case | S5 | Neg | Neg | ||||||
| Non-case | S6 | Neg | S. pyogenes |
*Sero, serotype; TAC, TaqMan Array Card; IPD, invasive pneumococcal disease; S, staff; rec, recovered; neg, negative; P, patient; pos, positive; NS, no carriage screen; V, visitor; NT, nontypeable; Unk, unknown. †TAC used to test for influenza viruses A (H1 and H3) and B, respiratory syncytial virus, human parainfluenza viruses 1–3, human metapneumovirus, rhinovirus, enterovirus, parechovirus, adenovirus, Legionella species, Haemophilus influenzae, Streptococcus pyogenes, Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Bordetella pertussis. ‡NT by real-time PCR (for serotypes: 1, 2, 3, 4, 5, 6A/B/C, 6C, 7F/7A, 9V/9A, 11A/11D, 12F/(12A/44/46), 14, 15A/15F, 16F, 18/(18A/18B/18C/18F), 19A, 19F, 22F/22A, 23A, 23F, 33F/33A/37). §Refused further involvement with investigation.