Table 1. Characteristics of 202 children hospitalized for adenovirus infection at National Taiwan University Hospital, by disease severity, Taipei City, Taiwan, November 2010–June 2011*.
| Characteristic | All | Severe infection, n = 31 | Nonsevere infection, n = 171 | p value |
|---|---|---|---|---|
| Median age, mo (range) | 40 (1–189) | 36 (1–185) | 41 (2–189) | 0.287 |
| Male sex | 115 (57) | 21 (68) | 94 (55) | 0.186 |
| Contact history | 119 (59) | 15 (48) | 104 (61) | 0.196 |
| Median hospitalization, d (range) | 5 (1–126) | 18 (4–126) | 5 (1–44) | <0.001 |
| Death rate | 7 (4) | 7 (23) | 0 (0) | <0.001 |
| Any underlying disease | 76 (38) | 24 (77) | 52 (30) | <0.001 |
| Prematurity | 36 (18) | 8 (26) | 28 (16) | 0.207 |
| Cardiopulmonary† | 31 (15) | 12 (39) | 19 (11) | <0.001 |
| Neurologic‡ | 25 (12) | 19 (61) | 6 (4) | <0.001 |
| Hematologic§ | 2 (1) | 1 (3) | 1 (0.6) | 0.284 |
| Metabolic¶ | 7 (4) | 4 (13) | 3 (2) | 0.012 |
| Immunodeficiency# | 1 (0.5) | 1 (3) | 0 (0) | 0.153 |
*Values are no. (%) patients except as indicated. Severe infection indicates patients who were admitted to the intensive care unit. †Congenital heart diseases (12), asthma (11), chronic lung disease (4), tracheobronchial stenosis (2), and laryngo-tracheo-bronchomalacia (2). ‡Cerebral palsy, epilepsy, and psychomotor retardation. §Acute myeloid leukemia and Burkitt’s leukemia. ¶Pompe disease, metachromatic leukodystrophy, glycogen storage disease, isovaleric acidemia, short-chain acyl-coA dehydrogenase deficiency, renal tubular acidosis, and mitochondrial disease. #Hypogammaglobulinemia.