Table 3. Laboratory test results for 202 children hospitalized for adenovirus infection at National Taiwan University Hospital, by disease severity, Taipei City, Taiwan, November 2010–June 2011*.
| Laboratory results and no. patients tested | All | Severe infection, n = 31 | Nonsevere infection, n = 171 | p value |
|---|---|---|---|---|
| Hemoglobin, g/dL (range), n = 201 | 11.7 | 9.7 (3.4–13.8) | 11.8 (7.0–14.6) | <0.001 |
| Platelets, × 103/μL (range), n = 201 | 237 | 106 (11–340) | 251(14–555) | <0.001 |
| Thrombocytopenia, no. (%) patients† | 43 (21) | 24 (77) | 19 (11) | <0.001 |
| Leukocytes, × 103 cells/μL (range), n = 201 | 10.06 | 4.4 (1.2–10.3) | 11.3 (0.2–35.5) | <0.001 |
| Leukopenia, no. (%) patients‡ | 28 (14) | 18 (58) | 10 (6) | <0.001 |
| Sodium, mmol/L (range), n = 138 | 135 | 131 (119–137) | 135 (127–142) | <0.001 |
| Hyponatremia, no. (%) patients§ | 68 (49) | 22 (81) | 46 (41) | <0.001 |
| C-reactive protein, mg/dL (range), n = 200 | 4.15 | 6.1 (0.02–30.00) | 4.0 (0–47.2) | 0.086 |
| LDH, U/L (range), n = 22 | 2,202 | 3,281 (1,029–9,782) | 937 (493–17,454) | 0.023 |
| AST, U/L (range), n = 117 | 43 | 135 (38–3,520) | 38 (3.5–989) | <0.001 |
| AST >2× upper limit, no. (%) patients | 36 (31) | 22 (85) | 14 (15) | <0.001 |
| ALT, U/L (range), n = 104 | 26.5 | 67.5 (12.0–511.0) | 24 (8–652) | <0.001 |
| ALT >2× upper limit, no. (%) patients | 24 (23) | 15 (58) | 9 (12) | <0.001 |
| Creatinine, mg/dL (range), n = 155 | 0.61 | 0.68 (0.3–1.1) | 0.6 (0.2–0.9) | 0.088 |
*Severe infection indicates patients who were admitted to the intensive care unit. LDH, lactate dehydrogenase; AST, aspartate aminotransferase; ALT, alanine aminotransferase. †Platelet count <150,000/μL. ‡Leukocyte count <5,000 cells/μL. §Serum sodium <135 mmol/L.