Table 1.

Binding of human monoclonal anti-NY-ESO-1 antibodies to NYESO-1. Comparison of EC₅₀ and equilibrium affinity constants for the binding between NY-ESO-1 and different anti-NY-ESO-1 antibodies.

Antibody	EC50 [pM] (prok. NY-ESO-1)	KD [M] (prok. NY-ESO-1)	KD [M] (euk. NY-ESO-1)
12D7	1.14	2.08×10−10	1.56×10−10
1D4	2.23	1.62×10−9	2.24×10−10
30D6	1.09	4.35×10−9	2.65×10−9
31E4	9.52	1.9×10−8	2.23×10−8
15B12	72.6	---	---
E978 control	6.66	2.56×10−8	1.56×10−11