Table 1.
Morphological and In Situ Tibialis Anterior Muscle Functional Characteristics
| |
2 months |
4 months |
||||
|---|---|---|---|---|---|---|
| Control (n=3) | Contra (n=5) | VML (n=5) | Control (n=3) | Contra (n=9) | VML (n=9) | |
| BW (g) | ||||||
| Pre | 320±3a | — | 349±5 | 318±5 | — | 343±3 |
| Final | 456±10 | — | 478±18 | 475±13 | — | 490±15 |
| MW | ||||||
| TA (mg) | 646±19a | 717±30 | 571±50b | 766±13 | 770±41 | 633±40b |
| TA/BW (mg/g) | 1.49±0.07 | 1.49±0.05 | 1.19±0.09b | 1.59±0.02 | 1.56±0.6 | 1.29±0.11b |
| EDL (mg) | 179±2 | 193±7 | 222±12b | 178±10 | 200±15 | 233±22 |
| EDL/TA | 27.3±0.5 | 26.6±1.0 | 39.3±2.3 | 23.7±0.6 | 25.8±1.7 | 37.0±4.8b |
| TA-Po | ||||||
| N | 10.7±1.1 | 11.9±0.7 | 9.0±0.9b | 12.1±1.3 | 12.8±1.3 | 9.2±1.8b |
| N/g of MW | 16.7±1.2 | 16.9±0.3 | 16.1±1.6 | 16.3±1.73 | 16.7±1.7 | 14.6±2.7 |
| mN/kg of BW | 24.9±1.6 | 23.9±1.5 | 18.7±0.6b | 25.6±1.8 | 25.9±2.4 | 18.8±3.4b |
All values are mean±standard deviation.
a
Significantly different from VML (p<0.05).
b
Significantly different from contralateral control (Contra) (p<0.05).
VML, volumetric muscle loss; BW, body weight; MW, muscle weight; TA, tibialis anterior; EDL, extensor digitorum longus; Po, peak isometric torque.