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. 2013 Jan 30;8(1):e55147. doi: 10.1371/journal.pone.0055147

Table 2. BCL11B expression induces FOS expression in the OMT cells.

Gene Symbol Gene Title Fold change
(mean±S.D)
FOS FBJ murine osteosarcoma viral oncogene homolog 8.3±5.3
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.5±0.4
FRA1 FOS-like antigen 1 1.3±0.4
FRA2 FOS-like antigen 2 1.2±0.3
JUN jun proto-oncogene 2.0±0.3
JUNB jun B proto-oncogene 1.0±0.3
JUND jun D proto-oncogene 1.0±0.4
BCL6 B-cell CLL/lymphoma 6 1.7±0.1
GATA3 GATA binding protein 3 1.0±0.2
TCF8 zinc finger E-box binding homeobox 1 2.0±0.4
IKAROS IKAROS family zinc finger 1 1.2±0.2
HELIOS IKAROS family zinc finger 2 1.6±0.4
FOXP3 forkhead box P3 0.7±0.2
PCNA proliferating cell nuclear antigen 1.1±0.4
CCND1 cyclin D2 0.9±0.3
CCND3 cyclin D3 1.2±0.2
CCNE1 cyclin E1 0.9±0.3
CCNA2 cyclin A2 0.9±0.2
CDK2 cyclin-dependent kinase 2 1.0±0.4
CDK4 cyclin-dependent kinase 4 1.0±0.4
E2F1 E2F transcription factor 1 1.0±0.5
E2F2 E2F transcription factor 2 0.9±0.5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.1±0.2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.0±0.2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) ND
TP53 tumor protein p53 1.3±0.4
IL2 interleukin 2 2.6±1.6
CCR4 chemokine (C-C motif) receptor 4 0.9±0.3
IL10 interleukin 10 ND
ICAM PTP1C intercellular adhesion molecule 1protein tyrosine phosphatase, non-receptor type 6 0.9±0.20.8±0.2
MYB v-myb myeloblastosis viral oncogene homolog (avian) 1.1±0.5
Tax HTLV-1 regulatory and accessory genes 1.2±0.4
HBZ HTLV-1 bZIP factor gene 1.0±0.3

The OMT cells were transfected with plasmids encoding GFP (control) or BCL11B-GFP. The cells with GFP fluorescence were isolated by FACS at 48 h after the transfection, and total RNA was extracted. The mRNA levels were quantified by RT-PCR, normalized to GAPDH and expressed relative to the GFP-expressing control cells.