Table 2. The odds ratios for breast cancer risk by plasma 25(OH)D concentration.
Plasma 25(OH)D | Cases | Controls | Crude model OR (95% CI) | Adjusted model* OR (95% CI) | ||
Categorized (ng/ml) | No. | % | No. | % | ||
Q1 (≤10.4) | 325 | 54.8 | 145 | 25.0 | 1.00 (Reference) | 1.00 (Reference) |
Q2 (10.4–13.4) | 148 | 25.0 | 145 | 25.0 | 0.44 (0.32–0.60) | 0.43 (0.31–0.60) |
Q3 (13.4–17.9) | 81 | 13.6 | 145 | 25.0 | 0.28 (0.19–0.39) | 0.24 (0.17–0.35) |
Q4 (>17.9) | 39 | 6.6 | 145 | 25.0 | 0.11 (0.07–0.17) | 0.10 (0.06–0.15) |
p-trend | <0.001 | <0.001 | ||||
Continuous | ||||||
per 1 ng/ml increment | 593 | 580 | 0.85 (0.82–0.88) | 0.84 (0.81–0.87) |
The OR was adjusted by age, age at first birth, age at menarche, use of contraceptive, menopausal status, first-degree relatives’ history of breast cancer and season of blood collection.