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. 2013 Jan 30;8(1):e51970. doi: 10.1371/journal.pone.0051970

Table 3. Association of IL-13 with asthma phenotypes, by additive genetic model.

SNP Asthma Wheeze Early-onset asthma Late-onset asthma
OR 95% CI P value FDR OR 95% CI P value FDR OR 95% CI P value FDR OR 95% CI P value FDR
rs1800925 1.2 (0.9,1.5) 0.21 0.41 1.3 (1.1,1.5) 0.01 0.03 1.2 (0.9,1.5) 0.23 0.60 1.2 (0.8,1.7) 0.41 0.76
rs2066960 0.9 (0.7,1.1) 0.12 0.41 0.9 (0.7,1.0) 0.02 0.04 1.0 (0.8,1.2) 0.60 0.60 0.7 (0.5,1.0) 0.03 0.13
rs20541 1.1 (0.9,1.3) 0.45 0.49 1.2 (1.0,1.4) 0.04 0.04 1.1 (0.9,1.4) 0.44 0.60 1.1 (0.8,1.5) 0.66 0.76
rs848 1.1 (0.9,1.3) 0.49 0.49 1.2 (1.0,1.4) 0.04 0.04 1.1 (0.9,1.3) 0.54 0.60 1.0 (0.8,1.4) 0.76 0.76

Models are adjusted for age, sex, parental history of asthma, parental history of atopy, in utero exposures to maternal smoking, ETS, dampness, incense burning, pet ownership at home and community.

Early-onset: asthma diagnosed ≦5 yr of age.

Late-onset: asthma diagnosed >5 yr of age.