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. 2013 Jan 30;8(1):e53630. doi: 10.1371/journal.pone.0053630

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© 2013 Kim et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Significant inverse correlation of Foxp3+ cancer cell expression with the Foxp3 Treg expression. Regression analysis; R², coefficient of determination. (B) Increased numbers of Foxp3+ Treg in Foxp3 negative cancer tissue (arrow). (C) Only occasionally or no Foxp3+ Treg in Foxp3 positive cancer tissue (arrow). DAB brown color, Haemalaun blue color – nuclear counterstaining. Representative example demonstrates area of magnifications x100 (left) and x200 (right).