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. 2013 Jan 30;8(1):e54994. doi: 10.1371/journal.pone.0054994

Table 2. Stratified analyses of 5-HTTLPR gene polymorphism on LPE risk.

Variables Na Cases/Controls Allelic contrast Homozygote comparison Heterozygote comparison Dominant genetic model
OR(95%CI) P b/P OR(95%CI) P b/P OR(95%CI) P b/P OR(95%CI) P b/P
Total 6 481/466 0.86(0.79–0.95)0.086/0.002 0.80(0.68–0.95)0.240/0.009 0.85(0.76–0.97)0.047/0.012 0.88(0.81–0.95)0.020/0.002
Ethnicity
Asian 1 119/90 0.64(0.43–0.96)−/0.029 0.54(0.27–1.08)−/0.080 0.61(0.32–1.16)−/0.133 1.47(0.77–2.78)−/0.067
Caucasian 5 362/376 0.88(0.80–0.98)0.086/0.015 0.83(0.70–1.00)0.228/0.046 0.88(0.77–1.00)0.040/0.043 0.90(0.83–0.98)0.024/0.015
Source of control
HB 2 208/182 0.91(0.78–1.06)0.039/0.229 0.87(0.66–1.15)0.077/0.339 0.93(0.75–1.15)0.083/0.518 0.93(0.80–1.07)0.032/0.294
PB 4 273/284 0.83(0.74–0.93)0.213/0.002 0.76(0.61–0.93)0.395/0.008 0.81(0.70–0.94)0.056/0.006 0.85(0.77–0.94)0.042/0.001