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. 2013 Jan 30;8(1):e54648. doi: 10.1371/journal.pone.0054648

Table 3. IC50 and Hill slope values for block of rat nAChR subtypes by αB-Conotoxin VxXXIVA [1], [2].

nAChR subtype IC50 IC50 C.I. Hill Slope Hill Slope C.I.
Rat α2β2 23.4 µM 17.3–31.5 µM 1.1 0.7–1.5
Rat α2β4 >30 µM
Rat α3β2 >30 µM
Rat α3β4 >30 µM
Rat α4β2 >30 µM
Rat α4β4 >30 µM
Rat α6/α3β2β3 12.2 µM 10.0–14.9 µM 1.2 0.9–1.7
Rat α6/α3β4 30.1 µM 18.8–48.0 µM 1.0 0.5–1.5
Rat α7 >30 µM
Rat α9α10 1.2 µM 0.8–1.7 µM 1.4 0.5–2.1
Mouse α1β1γδ 6.6 µM 5.1–8.5 µM 1.2 0.8–1.6

C.I., 95% confidence interval.