Leukocyte content of BALF 24 h after inoculation. Animals infected with wild-type bacteria and the isometric dose of the O-antigen mutant had comparable numbers of leukocytes (P, not significant). However, animals infected with the isolethal dose of the mutant strain had significantly greater leukocyte influx into the lung (P < 0.05 by analysis of variance). Boxes represent 25th, 50th, and 75th percentiles. Whiskers represent the total range of measured values. For wild type, n = 4; for both mutant groups, n = 5.