Kinetic analysis. CFU per gram of tissue in the PP (A), MLN (B), and spleens (C) of mice infected for 1, 3, or 7 days are shown. Results from two independent experiments were combined. Analysis was performed in duplicate for each mouse strain (C57BL/6j, dose 1 = 8 × 108 and dose 2 dose = 1 × 108; BALB/cj, dose 1 = 1 × 108 and dose 2 = 5 × 108); 129X1/Svj, dose 1 = 5 × 108 and dose 2 = 5 × 108). The limit of detection for each tissue is indicated by a dashed line. Nonparametric ANOVA using the Kruskal-Wallis statistic and Dunns post-test was used to compare mean CFU/gram of tissue for each day. Symbols at the limit of detection represent mice that survived but did not have detectable numbers of bacteria. Two C57BL/6j mice died by day 7.