FIG. 5.

Proliferation of pleural exudate cells from pleuritic guinea pigs in control and anti-TGF-β1-treated groups. Pleural exudate cells from guinea pigs with experimental tuberculous pleurisy were cultured for 96 h in the presence of 10 μg of ConA per ml, 12.5 μg of PPD per ml (PPD-12.5), or 25 μg of PPD per ml (PPD-25). Proliferative responses are expressed as the stimulation index (counts per minute for stimulated cells/counts per minute for unstimulated cells) for individual animals. The bars indicate the means for three or four animals, and the error bars indicate the standard errors of the means. An asterisk indicates that the proliferative response is significantly greater than that of cells from control guinea pigs.