Fig. 2.

(A–C) Percentage of nuclei expressing MFRs. Plots show median values with interquartile range. Continuous bars show significant differences between disease groups and controls, dotted bars demonstrate variations between disease groups. (A) Pax7⁺ SCs, ^∗p < 0.0001; ^∗∗p = 0.003; ^∗∗∗p = 0.016. (B) MyoD⁺ nuclei, ^∗p < 0.0001; ^∗∗p = 0.001; ^∗∗∗p = 0.016; ^∗∗∗∗p < 0.0001. (C) Myogenin⁺ nuclei, ^∗p < 0.0001; ^∗∗p = 0.008; ^∗∗∗p = 0.001; ^∗∗∗∗p = 0.018. (D–F) Percentage of muscle fibers expressing markers of regeneration. (D) Neonatal myosin⁺ fibers, ^∗p < 0.0001; ^∗∗p = 0.001; ^∗∗∗p = 0.042, ^∗∗∗∗p = 0.003. (E) Vimentin⁺ fibers, ^∗p < 0.0001; ^∗∗p = 0.031; ^∗∗∗p = 0.001. (F) NCAM⁺ fibers, ^∗p < 0.0001; ^∗∗p = 0.001; ^∗∗∗p = 0.024. (G) Significant correlation between the frequency of CD68⁺ mononuclear cells and Pax7⁺ SCs (R = 0.561).