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. 2004 Mar;72(3):1594–1602. doi: 10.1128/IAI.72.3.1594-1602.2004

TABLE 1.

Comparison of routes of immunization

Vaccine Route Relative parasite burdena Immunofluorescent antibody titer
Sporozoiteb Blood stageb Liver stagec
PY00835 Gene gun −0.1 2,560 20 ND
IM 0.3 Neg Neg ND
PY01316 Gene gun −1.3* 2,560 20 Neg
IM 0.5 Neg Neg ND
PY01828 Gene gun 0.1 2,560 640 Pos
IM 0.1 Neg Neg ND
CSP Gene gun −0.1 2,560 Neg Neg
IM −2.7* 2,560 Neg ND
a

Parasite burden in liver is in comparison with that in challenged unvaccinated mice and is expressed as log10. *, parasite burden significantly different (P < 0.05) versus that in challenged unvaccinated mice.

b

Shown are the antibody titers from pooled antisera. Values are the last dilution at which florescence was detected. Neg, negative; Pos, positive; ND, not done.

c

Sera tested at a single dilution (1:80).