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Exogenous IFN-α/β or -γ improves viability in B. anthracis-infected macrophages. Human AM were incubated with the Sterne strain (34F2) with either IFN-β at 1,000 U/ml (A), IFN-γ at 400 U/ml (B), or saline at an MOI of 20:1 for 4.5 h. Viability was determined by WST-1 assay. Results are expressed as changes in viability relative to uninfected controls. Results represent 10 to 15 replicates. Error bars, standard deviations. ★, P = 0.009; ⧫, P = 0.03.
