TABLE 3.

Populations of purified CD8⁺ T lymphocytes that traverse HUVEC are not markedly enriched for cells that secrete IFN-γ

Donora	% of CD8+ T lymphocytes secreting IFN-γ
	Initial population	Migrated across unstimulated HUVEC	Migrated across IL-1β-treated HUVECb	Migrated across B. burgdorferi-treated HUVECb,c
A	23	63	57	64
B	33	60	54	61
C	69	69	66	78
D	30	27	38	51

^aThe donors correspond to those used for the experiments in Table 1, but the T cells were isolated on different days.

^bOn average, 1.7 ± 0.2-fold more T lymphocytes traversed stimulated HUVEC than unstimulated endothelium in these experiments.

^cThe population of CD8⁺ T lymphocytes that migrated across B. burgdorferi-activated endothelium showed significant enrichment for cells that secrete IFN-γ compared to the initial population (P < 0.05).