TABLE 4.
Distribution of Cases According to Braak Stages and Neuritic Amyloid Plaque Densities
| Neuritic Aβ Plaque Density
|
||||
|---|---|---|---|---|
| None | Sparse | Moderate | Frequent | |
| Braak staging (NFTs) | ||||
| 0 | 52 | 14 | 10 | 3 |
| I | 79 | 24 | 31 | 7 |
| II | 68 | 59 | 48 | 17 |
| III | 48 | 59 | 108 | 64 |
| IV | 22 | 41 | 160 | 158 |
| V | 0 | 25 | 134 | 553 |
| VI | 3 | 14 | 72 | 1,035 |
Data are from the National Alzheimer’s Coordinating Center (n = 2,903 included, as described previously [282]) to show distribution of cases according to Braak stages (0 to VI) of neurofibrillary tangles (NFTs) (60) and neuritic amyloid (Aβ) plaque densities, graded according to Consortium to Establish A Registry for Alzheimer’s Disease criteria (51).