Figure 6. Schematic model of the free energy landscape of the S1 - S2 transitions of the FhuA ΔC/Δ4L – bilayer system.

Continue and dashed lines denote the free energy landscape at the applied transmembrane potential of 40 and 180 mV, respectively. Thin and thick lines indicate the data for the Bcyl and Bcon bilayers, respectively. The two horizontal dashed lines show the energetic minima of the S2 state at low (40 mV) and high (180 mV) positive voltages.