Table 1.
Characteristics of 13,415 African-American participants from ten cohort studies.a
| Variableb | ARIC n=2,391 |
BLSA n=155 |
BHS n=191 |
CFS n=267 |
CHS n=674 |
HABCc n=1,054 |
HANDLS n=945 |
JHS n=1,962 |
MESA n=1,627 |
WHIc n=4,149 |
|---|---|---|---|---|---|---|---|---|---|---|
| PR interval (ms) | 172 ± 27 | 172 ± 25 | 161 ± 23 | 169 ± 26 | 172 ± 29 | 171 ± 28 | 162 ± 25 | 171 ± 26 | 171 ± 26 | 167 ± 25 |
| RR interval (ms) | 923 ± 150 | 957 ± 130 | 896 ± 149 | 903 ± 131 | 921 ± 158 | 931 ± 154 | 907 ± 154 | 949 ± 148 | 975 ± 155 | 915 ± 146 |
| Age (years) | 53.2 ± 8.8 | 64.4 ± 11.4 | 35.7 ± 4.8 | 44.3 ± 15.2 | 72.6 ± 5.5 | 73.4 ± 2.9 | 48.6 ± 9.0 | 49.3 ± 11.7 | 62.1 ± 10.1 | 61.6 ± 6.8 |
| Female sex (%) | 1,480 (62) | 98 (63) | 127 (66) | 154 (58) | 431 (64) | 609 (58) | 527 (56) | 1,203 (61) | 887 (55) | 4,149 (100) |
| BMI (kg/m2) | 29.5 ± 6.1 | 28.3 ± 5.2 | 31.5 ± 8.7 | 34.5 ± 9.2 | 28.4 ± 5.5 | 28.5 ± 5.4 | 29.9 ± 8.1 | 32.3 ± 7.8 | 30.2 ± 5.9 | 31.6 ± 6.2 |
| Systolic BP (mmHg) | 128.1 ± 20.7 | 133.7 ± 15.6 | 124.3 ± 17.9 | 126.1 ± 14.4 | 146.2 ± 21.5 | 138.7 ± 22.0 | 120.8 ± 21.9 | 124.6 ± 17.8 | 131.6 ± 21.6 | 131.9 ± 17.3 |
| Genomic inflation factor (λ) | 1.023 | 0.969 | 0.989 | 1.099 | 1.043 | 1.014 | 0.947 | 1.079 | 1.008 | 1.010 |
| % European ancestryd | 15 (11, 22) | ND | 18 (13, 21) | 18 (13, 26) | 24 (16, 36) | 19 (12, 28) | 16 (11, 22) | 16 (12, 21) | 19 (12, 30) | 21 (13, 31) |
Sample sizes presented are the maximum number of participants with SNP data.
Data are presented as mean (standard deviation) for continuous variables and percentages for categorical variables.
The HABC and WHI studies replaced imputed data with genotyped data when available and therefore have a range of genotyped participants (HABC minimum = 939 participants; WHI minimum = 3,898 participants).
Presented as median (25th percentile, 75th percentile)
ARIC, Atherosclerosis Risk in Communities; BLSA, Baltimore Longitudinal Study on Aging; BHS, Bogalusa Heart Study; CFS, Cleveland Family Study; CHS, Cardiovascular Health Study; HABC, The Health, Aging, and Body Composition Study; HANDLS, The Healthy Aging in Neighborhoods of Diversity across the Life Span Study; JHS, Jackson Heart Study; MESA, Multi-Ethnic Study of Atherosclerosis; ND, not determined. WHI, Women’s Health Initiative.