Table 4.
Baseline and postinterventional concentrations of vasoconstrictors, tissue factor, and TNFα
| |
With DM |
Without DM |
||
|---|---|---|---|---|
| Coronary arterial plasma | Coronary aspirate plasma | Coronary arterial plasma | Coronary aspirate plasma | |
|
catecholamines, n = 12 / 12 |
|
|
|
|
| epinephrine [nmol/L] |
0.4 ± 0.1 |
0.4 ± 0.1 |
0.4 ± 0.1 |
0.4 ± 0.1 |
| norepinephrine [nmol/L] |
3.2 ± 0.8 |
3.7 ± 0.6 |
3.4 ± 0.9 |
4.1 ± 1.3 |
|
endothelin [pmol/L], n = 15 / 16 |
1.4 ± 0.6 |
1.3 ± 0.5 |
1.9 ± 0.6 |
1.7 ± 0.6 |
|
serotonin [μmol/L], n = 15 / 16 |
0.5 ± 0.2 |
0.9 ± 0.4† |
0.4 ± 0.1 |
1.1 ± 0.5† |
|
thromboxane B2[pmol/L], n = 15 / 16 |
46 ± 7 |
95 ± 9† |
51 ± 8 |
82 ± 13† |
|
tissue factor [pmol/L], n = 15 / 16 |
8.6 ± 0.5 |
8.7 ± 0.6 |
9.6 ± 1.0 |
8.8 ± 0.8 |
| TNFα [pmol/L], n = 15 / 16 | 1.1 ± 0.3 | 2.2 ± 0.7*, † | 0.5 ± 0.2 | 1.1 ± 0.2† |
Data are mean±SEM. Comparison by 2-way repeated measures ANOVA with Bonferroni’s correction; *P<0.05 with vs. without DM, †P<0.05 coronary arterial plasma vs. coronary aspirate plasma. DM = diabetes mellitus; TNFα = tumor necrosis factor α.