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. 2012 Dec 4;4(11):790–802. doi: 10.18632/aging.100506

Figure 4. Decreased helicase activity correlates with lower ATPase activity.

Figure 4

(A) Representative gel showing ATPase activity of WT and mutants, at 0, 20, 40, and 80 nM protein. (B) ATPase data compiled from triplicate experiments. The activities of P466L, F697L and in particular F637S are significantly reduced compared to wild-type (at 50%, 65% and 9% of WT at 80 nM protein, respectively). *, †, and ‡ denote p < 0.05 between WT and P466L, F637S and F697L, respectively. Error bars represent standard error of mean from three experiments.