Table 4.
Associations of Eph-A2 and Eph-A4 expression with clinicopathological characteristics in patients with malignant thyroid lesions
| Clinicopathological Characteristics | Eph-A2 expression | Eph-A4 expression | ||||||
|---|---|---|---|---|---|---|---|---|
| Negative/weak | Moderate | Strong | p-valuea | Negative/weak | Moderate | Strong | p-valuea | |
| N=59 | 15 (25.4) | 24 (40.7) | 20 (33.9) | 22 (37.3) | 9 (15.2) | 28 (47.5) | ||
| Tumor size (T) | 0.481 | 0.510 | ||||||
| T1 | 11 (27.5) | 14 (35) | 15 (37.5) | 14 (35) | 6 (15) | 20 (50) | ||
| T2 | 4 (30.8) | 6 (46.2) | 3 (23) | 7 (53.8) | 2 (15.4) | 4 (30.8) | ||
| T3 | 0 (0) | 1 (33.3) | 2 (66.7) | 1 (33.3) | 0 (0) | 2 (66.6) | ||
| T4 | 0 (0) | 3 (100) | 0 (0) | 0 (0) | 1 (33.3) | 2 (66.6) | ||
| TNM staging | 0.953 | 0.898 | ||||||
| I | 10 (25) | 15 (37.5) | 15 (37.5) | 13 (32.5) | 7 (17.5) | 20 (50) | ||
| II | 3 (37.5) | 4 (50) | 1 (12.5) | 5 (62.5) | 0 (0) | 3 (37.5) | ||
| III | 2 (25) | 2 (25) | 4 (50) | 4 (50) | 1 (12.5) | 3 (37.5) | ||
| IV | 0 (0) | 3 (100) | 0 (0) | 0 (0) | 1 (33.3) | 2 (66.6) | ||
| Capsular invasion | 0.287 | 0.232 | ||||||
| Negative | 9 (22.5) | 14 (36.8) | 15 (37.5) | 11 (28.9) | 7 (18.4) | 20 (52.6) | ||
| Positive | 2 (20) | 4 (40) | 4 (40) | 2 (20) | 1 (10) | 7 (70) | ||
| Lymphatic invasion | 0.313 | 0.964 | ||||||
| Negative | 9 (23.1) | 16 (40) | 15 (38.5) | 11 (27.5) | 6 (15.0) | 23 (57.5) | ||
| Positive | 2 (25) | 2 (25) | 4 (50) | 2 (25) | 2 (25) | 4 (50) | ||
| Vessel invasion | 0.659 | 0.799 | ||||||
| Negative | 10 (25) | 15 (37.5) | 19 (47.5) | 12 (27.3) | 7 (15.9) | 25 (56.8) | ||
| Positive | 1 (25) | 2 (50) | 1 (25) | 0 (0) | 1 (20) | 3 (60) | ||
| Ki67 protein statement | 0.433 | 0.091 | ||||||
| < Mean value | 3 (30) | 4 (40) | 3 (30) | 3 (30) | 3 (30) | 4 (40) | ||
| ≥ Mean value | 12 (24.5) | 20 (40.8) | 17 (34.7) | 19 (38.8) | 6 (12.2) | 24 (49) | ||
a
Pearson’s chi-square test.