TABLE 3 .
DE candidate novel microRNAs at 24 hpi
| Sequence | Locationa | Annotationb | Avg read countc |
Padjd | |
|---|---|---|---|---|---|
| Mock24 | HIV24 | ||||
| GUCCCUGUUCGGGCGCCAe | chr6:131375689.131375757: + | EPB41L2 intron | 1795.5 | 171.9 | 5.2 × 10−9 |
| UUAGUGGCUCCCUCUGCCUGCA | chr19:57950479.57950538: + | ZNF749 intron | 138.1 | 27.8 | 2.4 × 10−3 |
| GUCCCUGUUCAGGCGCCA | chr12:69593921.69593965: − | Intergenic | 37.8 | 5.2 | 5.0 × 10−3 |
| UGUAUGUAUGUAGACGUAUAUC | chr17:43642608.43642668: − | Intergenic | 32.3 | 3.7 | 5.6 × 10−3 |
| UGCCCUGAGACUUUUGCUCUAA | chr3:127305953.127306019: − | TPRA1 intron | 36.2 | 6.9 | 2.6 × 10−2 |
| UCACGUCCCUGUUCGGGCGCCA | chr19:58024383.58024432: − | Intergenic | 2138.6 | 854.3 | 3.1 × 10−2 |
a
Genomic position and strand of predicted pre-microRNA hairpin structure.
b
RefSeq mRNA annotation overlapping with given locations.
c
Average, normalized read counts for mock- and HIV-infected replicates at 24 hpi.
d
P values generated by DESeq and adjusted for total detected candidate novel microRNAs.
e
Bold indicates candidate microRNA chosen for follow-up analysis.