Figure 3.
Protein-DNA contacts. (a) Protein-DNA contacts in the wild-type product complex. Hydrogen bond/ionic interactions (dashed lines, 3.75Å cut-off), main chain amide nitrogen atoms (N) and steric interactions (orange arcs, 4.25Å cut-off) involving side chains (yellow circles) are shown for one of the two EndoV molecules binding symmetrically to the DNA. (b) Close-up of the coordination around the phosphodiester insicion. (c) Close-up of the strand separating PYIP-wedge with selected distances to DNA bases stacking with residues defining the protein surface. The hypoxanthine (dark red) is partially buried behind the wedge.