Table 1.
Drug | K562 IC50 (μg·mL−1) | K562/Dox IC50 (μg·mL−1) | RI of SB202190 group | RI of verapamil group | ||
---|---|---|---|---|---|---|
Control | SB202190 | Verapamil | ||||
Phenytoin | 468.82±44.67 | 2186.33±214.70 | 949.83±131.31 | 852.83±105.44 | 2.30 | 2.56 |
Doxorubicin | 0.32±0.05 | 4.33±0.50 | 0.40±0.09 | 0.35±0.05 | 10.83 | 12.37 |
Data represented as mean ±SD (n=12).