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FIG. 1.

FIG. 1.

Protection against vertical transmission of N. caninum tachyzoites in pups born from mothers immunized directly with pNcGRA7 or pNR plasmid DNA with or without CpG adjuvant. Control groups that were challenged with N. caninum tachyzoites included pups born from dams immunized with NcTZ vaccine (positive vaccine) or PBS [PBS(+), negative vaccine]) PBS(−) controls were not challenged with N. caninum tachyzoites. Treatments labeled with different letters are statistically different (P < 0.05) by exact binary logistic regression analysis.