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. 2004 Mar;72(3):1479–1486. doi: 10.1128/IAI.72.3.1479-1486.2004

FIG. 1.

FIG. 1.

Growth of Cftr-knockout mice and wild-type mice. Cftr-knockout mice (closed squares) (n = 14 to 15/time point), their homozygous wild-type littermates (closed circles) (n = 34 to 36/time point), and gut-corrected Cftr-knockout mice (open triangles) (n = 33 to 37/time point) were weighed weekly starting at 1 week of age. Data are expressed as means ± standard deviations. Cftr-knockout mice weighed significantly less than the wild-type or gut-corrected Cftr-knockout mice at 1 (3.0 ± 0.6, 4.5 ± 0.7, and 5.0 ± 1.0 g, respectively), 2 (5.8 ± 0.9, 8.1 ± 1.1, and 8.2 ± 1.4 g, respectively) and 3 weeks (7.0 ± 1.1, 11.0 ± 1.8, and 11.3 ± 1.9 g, respectively) of age. An asterisk (*) indicates a result that is significantly different from that for wild-type and gut-corrected Cftr-knockout mice (one-way ANOVA and pairwise comparisons made by using a Tukey test; P < 0.001).