Table 1.
Drugs | Doses (mg/kg) | No. of rats | Volume (mL) | Gastric pH |
---|---|---|---|---|
Control | – | 5 | 6.38±0.87 | 1.30±0.05 |
L-arginine | 250 | 4 | 6.30±0.41 | 1.82±0.05* |
L-alanine | 500 | 5 | 8.56±0.48 | 2.36±0.12* |
L-glutamine | 750 | 5 | 8.66±0.81 | 1.73±0.09* |
Glycine | 750 | 4 | 8.63±0.41 | 2.38±0.07* |
Amino acids were given orally immediately after the pylorus was ligated. The gastric contents were collected 3 h after the ligation. Following centrifugation for 10 min at 3,000 rpm, the volume of each sample was measured, and the pH was determined by using a pH meter. Values are presented as the mean ±SE for four to five rats.
Significant difference from control at P<0.05.